METHOD FOR PRODUCING A PLANT EXTRACT AND FRACTION, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF

METHOD FOR PRODUCING A PLANT EXTRACT AND FRACTION, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF

The present invention describes the obtaining process of the dichloromethane fraction and subfractions from Eleutherine plicata, popularly known as "marupazinho, maruparí, palmeirinha, coquinho, marupaí, marupaú, marupá-piranga, and lírio-folha-de-palmeira". This invention comprises the ob...

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Hauptverfasser: POVOA, MARINETE MARINS, MARTINS, MICHEL T, OLIVEIRA, ALAIDE BRAGA DE, BRANDAO, GERALDO CELIO, MARINHO, ANDREY MOACIR DO R, COELHO-FERREIRA, MARLIA REGINA, BUSMAN, DAMARIS, VASCONCELOS, FLAVIO DE, NASCIMENTO, MARIA FERNANDA ALVES DO, DOLABELA, MARIA FANI, BRANDAO, DAYSE LUCIA DO NASCIMENTO, SILVA, THIAGO L. DA, BORGEZ, EDINILZA DA SILVA, SILVA, ADRIANA VEIGA DA CONCEICAO, VILHENA, THYAGO DA COSTA, PAULA, RENATA CRISTINA DE, PERCARIO, SANDRO, MOTA, EDUARDO F
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention describes the obtaining process of the dichloromethane fraction and subfractions from Eleutherine plicata, popularly known as "marupazinho, maruparí, palmeirinha, coquinho, marupaí, marupaú, marupá-piranga, and lírio-folha-de-palmeira". This invention comprises the obtaining process of pharmaceutical compositions that contain the dichloromethane fraction and/or naphthoquinone, as well as its use for malaria treatment. Extract and fractions were assayed and presented antiplasmodial activity, particularly against chloroquine-resistant Plasmodium falciparum (clone W2).