TARGETED IMMUNOCONJUGATES

The present invention relates to immunoconjugates. In particular embodiments, the present invention relates to immunoconjugates comprising at least one single-chain effector moiety and two or more antigen binding moieties. In addition, the present invention relates to nucleic acid molecules encoding...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SILACCI-MELKKO MICHELA, UMANA PABLO, HOSSE RALF, MOESSNER EKKEHARD
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to immunoconjugates. In particular embodiments, the present invention relates to immunoconjugates comprising at least one single-chain effector moiety and two or more antigen binding moieties. In addition, the present invention relates to nucleic acid molecules encoding such immunoconjugates, vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the immunoconjugates of the invention, and to methods of using these immunoconjugates in the treatment of disease.