COMPOUNDS THAT ARE ERK INHIBITORS

Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.

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Hauptverfasser: ZHU HUGH Y, PATEL MEHUL F, KELLY JOSEPH M, NAN YANG, DENG YONGQI, WANG JAMES J-S, PALIWAL SUNIL, DESAI JAGDISH A, ALHASSAN ABDUL-BASIT, DOLL RONALD J, SHIH NENG-YANG, YAO XIN, ZHU LIANG, COOPER ALAN B, GAO XIAOLEI, TSUI HONUNG, SHIPPS JR GERALD W, BOGA SOBHANA BABU, GUDIPATI SUBRAHMANYAM
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.