15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID Y-LACTONE DERIVATIVE,USE THEREOF,AND MEDICAMENT CONTAINING SAID DERIVATIVE
The invention relates to 15,16-methylene-17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the general chemical formula I, and R4, R6a, R6b, R7 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the...
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| creator | MENGES FREDERIK KUHNKE JOACHIM RING SVEN FRENZEL THOMAS PRELLE KATJA BOHLMANN ROLF KLAR ULRICH MUHN HANS-PETER BORDEN STEFFEN HUBNER JAN |
| description | The invention relates to 15,16-methylene-17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the general chemical formula I, and R4, R6a, R6b, R7 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action. |
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The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STEROIDS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140129&DB=EPODOC&CC=ZA&NR=201005394B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140129&DB=EPODOC&CC=ZA&NR=201005394B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MENGES FREDERIK</creatorcontrib><creatorcontrib>KUHNKE JOACHIM</creatorcontrib><creatorcontrib>RING SVEN</creatorcontrib><creatorcontrib>FRENZEL THOMAS</creatorcontrib><creatorcontrib>PRELLE KATJA</creatorcontrib><creatorcontrib>BOHLMANN ROLF</creatorcontrib><creatorcontrib>KLAR ULRICH</creatorcontrib><creatorcontrib>MUHN HANS-PETER</creatorcontrib><creatorcontrib>BORDEN STEFFEN</creatorcontrib><creatorcontrib>HUBNER JAN</creatorcontrib><title>15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID Y-LACTONE DERIVATIVE,USE THEREOF,AND MEDICAMENT CONTAINING SAID DERIVATIVE</title><description>The invention relates to 15,16-methylene-17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the general chemical formula I, and R4, R6a, R6b, R7 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. 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The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS |
| title | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID Y-LACTONE DERIVATIVE,USE THEREOF,AND MEDICAMENT CONTAINING SAID DERIVATIVE |
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