4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS

4-IMIDAZOLIDINONES AS KV1.5 POTASSIUM CHANNEL INHIBITORS

The present teachings relate to 4-imidazolidinones of Formula (Ia) or (Ib) which are useful as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic activity. The present teachings further relate to compositions and methods for treating atrial-selective antiarrhythmia.

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Bibliographische Detailangaben
Hauptverfasser: BLASS BENJAMIN E, JANUSZ JOHN MICHAEL, RIDGEWAY JAMES M II, WU SHENGDE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present teachings relate to 4-imidazolidinones of Formula (Ia) or (Ib) which are useful as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic activity. The present teachings further relate to compositions and methods for treating atrial-selective antiarrhythmia.