Process for producing 1-(3,4-Dichlorobenzyl)-5-Octylbiguanide or a salt thereof

Process for producing 1-(3,4-Dichlorobenzyl)-5-Octylbiguanide or a salt thereof

The present invention provides a process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof, the process comprising reacting 1-cyano-3-octylguanidine or a salt thereof, with 3,4-dichlorobenzylamine or a salt thereof, in an ester-based organic solvent. According to the present in...

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Bibliographische Detailangaben
Hauptverfasser: MUGURUMA, YASUAKI, TSUJIMORI, HISAYUKI, NOMI, DAISUKE, TSUJI, KOICHI, YAMAGUCHI, TAIZO, TADA, NOBUHITO, OKAICHI, YOSHIHIKO, FUJITA, NOBUHISA
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides a process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof, the process comprising reacting 1-cyano-3-octylguanidine or a salt thereof, with 3,4-dichlorobenzylamine or a salt thereof, in an ester-based organic solvent. According to the present invention, the reaction can be carried out at a low temperature using general-purpose equipment, and 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof can be produced in a high yield by a safe and easy process.