Thiazole compounds as protein kinase B (PKB) Inhibitors
The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.
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creator | WOHLHIETER, GEORGE E WANG, XIANGHONG HUANG, XIN RIDER, JAMES T LIU, QINGYIAN VISWANADHAN, VELLARKAD N LI, AIWEN LEE, MATTHEW R FOTSCH, CHRISTOPHER H YUAN, CHESTER CHENGUANG ZENG, QINGPING HAH, NIANHE WEILER, KURT E YAO, GUOMIN BOURBEAU, MATTHEW P DOMINGUEZ, CELIA TASKER, ANDREW S ALLEN, JOHN G TADESSE, SEIFU HONG, FANG-TSAO |
description | The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein. |
format | Patent |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Thiazole compounds as protein kinase B (PKB) Inhibitors |
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