Thiazole compounds as protein kinase B (PKB) Inhibitors

The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.

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Bibliographische Detailangaben
Hauptverfasser:	WOHLHIETER, GEORGE E, WANG, XIANGHONG, HUANG, XIN, RIDER, JAMES T, LIU, QINGYIAN, VISWANADHAN, VELLARKAD N, LI, AIWEN, LEE, MATTHEW R, FOTSCH, CHRISTOPHER H, YUAN, CHESTER CHENGUANG, ZENG, QINGPING, HAH, NIANHE, WEILER, KURT E, YAO, GUOMIN, BOURBEAU, MATTHEW P, DOMINGUEZ, CELIA, TASKER, ANDREW S, ALLEN, JOHN G, TADESSE, SEIFU, HONG, FANG-TSAO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.