Mitotic kinesin inhibitors and methods of use thereof

Mitotic kinesin inhibitors and methods of use thereof

This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the tr...

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Hauptverfasser: LYSSIKATOS, JOSEPH P, DELISLE, ROBERT KIRK, HANS, JEREMY, CORRETTE, CHRISTOPHER P, LAIRD, ELLEN, ALLEN, SHELLEY, VOEGTLI, WALTER CHARLES, WALLACE, ELI M, ROBINSON, JOHN E, ZHAO, QIAN
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Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator LYSSIKATOS, JOSEPH P
DELISLE, ROBERT KIRK
HANS, JEREMY
CORRETTE, CHRISTOPHER P
LAIRD, ELLEN
ALLEN, SHELLEY
VOEGTLI, WALTER CHARLES
WALLACE, ELI M
ROBINSON, JOHN E
ZHAO, QIAN
description This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Mitotic kinesin inhibitors and methods of use thereof
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