Mitotic kinesin inhibitors and methods of use thereof

Mitotic kinesin inhibitors and methods of use thereof

This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LYSSIKATOS, JOSEPH P, DELISLE, ROBERT KIRK, HANS, JEREMY, CORRETTE, CHRISTOPHER P, LAIRD, ELLEN, ALLEN, SHELLEY, VOEGTLI, WALTER CHARLES, WALLACE, ELI M, ROBINSON, JOHN E, ZHAO, QIAN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders.