Process for making trans-1((1R, 3S)-6-chloro-3-pheny, lindan-1-yl)-3, 3-dimethylpiperazine

Process for making trans-1((1R, 3S)-6-chloro-3-pheny, lindan-1-yl)-3, 3-dimethylpiperazine

Described is a method for making the trans-1-((1R,3S)-6-chloro-3-phenylin-dan-1-yl)-3,3-dimethylpiperazine (formula I) and salts thereof and a similar method for making 4-((1R,3S)-6-chloro-3-phenylin-dan-1-yl)-1,2,2-trimethylpiperazine (formula IX) and salts thereof, which method comprises conversio...

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Bibliographische Detailangaben
Hauptverfasser: ROBIN, DAVID, BROESEN, PETER, WOEHLK NIELSEN, CHRISTINA, DAHL, ALLAN CARSTEN, SUTEU, CRISTINA
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Described is a method for making the trans-1-((1R,3S)-6-chloro-3-phenylin-dan-1-yl)-3,3-dimethylpiperazine (formula I) and salts thereof and a similar method for making 4-((1R,3S)-6-chloro-3-phenylin-dan-1-yl)-1,2,2-trimethylpiperazine (formula IX) and salts thereof, which method comprises conversion of a compound of formula IVa to the compound of formula I or the compound of formula IX, respectively.