6-Substituted 2,3,4,5-tetrahydro-1H-benzo[D]azepines as 5-HT2C receptor agonists
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT 2C receptor agonists for the treatment of 5-HT 2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: where: R 6 is -S-L-R 15 and other subst...
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| creator | SIEDEM, CHRISTOPHER STEPHEN BRINER, KARIN SINGH, AJAY MARTINE-GRAU, MAIA ANGELES ALLEN, JOHN GORDON COHEN, MICHAEL PHILIP RODRIGUEZ MICHAEL JOHN REINHARD, MATTHEW ROBERT TIDWELL, MICHAEL WADE BOYD, STEVEN ARMEN MAZANETZ, MICHAEL P CONWAY, RICHARD GERARD HELLMAN, SARAH LYNNE LEE, WAIY-MAN ROTHHAAR, ROGER RYAN GALKA, CHRISTOPHER STANLEY WILLIAMS, ANDREW CAERWYN DEO, ARUNDHATI S ZHANG, DEYI VICTOR, FRANTZ |
| description | The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT 2C receptor agonists for the treatment of 5-HT 2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety:
where:
R 6 is -S-L-R 15
and other substituents are as defined in the specification. |
| format | Patent |
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where:
R 6 is -S-L-R 15
and other substituents are as defined in the specification.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080227&DB=EPODOC&CC=ZA&NR=200606580B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080227&DB=EPODOC&CC=ZA&NR=200606580B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SIEDEM, CHRISTOPHER STEPHEN</creatorcontrib><creatorcontrib>BRINER, KARIN</creatorcontrib><creatorcontrib>SINGH, AJAY</creatorcontrib><creatorcontrib>MARTINE-GRAU, MAIA ANGELES</creatorcontrib><creatorcontrib>ALLEN, JOHN GORDON</creatorcontrib><creatorcontrib>COHEN, MICHAEL PHILIP</creatorcontrib><creatorcontrib>RODRIGUEZ MICHAEL JOHN</creatorcontrib><creatorcontrib>REINHARD, MATTHEW ROBERT</creatorcontrib><creatorcontrib>TIDWELL, MICHAEL WADE</creatorcontrib><creatorcontrib>BOYD, STEVEN ARMEN</creatorcontrib><creatorcontrib>MAZANETZ, MICHAEL P</creatorcontrib><creatorcontrib>CONWAY, RICHARD GERARD</creatorcontrib><creatorcontrib>HELLMAN, SARAH LYNNE</creatorcontrib><creatorcontrib>LEE, WAIY-MAN</creatorcontrib><creatorcontrib>ROTHHAAR, ROGER RYAN</creatorcontrib><creatorcontrib>GALKA, CHRISTOPHER STANLEY</creatorcontrib><creatorcontrib>WILLIAMS, ANDREW CAERWYN</creatorcontrib><creatorcontrib>DEO, ARUNDHATI S</creatorcontrib><creatorcontrib>ZHANG, DEYI</creatorcontrib><creatorcontrib>VICTOR, FRANTZ</creatorcontrib><title>6-Substituted 2,3,4,5-tetrahydro-1H-benzo[D]azepines as 5-HT2C receptor agonists</title><description>The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT 2C receptor agonists for the treatment of 5-HT 2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety:
where:
R 6 is -S-L-R 15
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where:
R 6 is -S-L-R 15
and other substituents are as defined in the specification.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 6-Substituted 2,3,4,5-tetrahydro-1H-benzo[D]azepines as 5-HT2C receptor agonists |
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