Method of obtaining citalopram

Process for preparing purified citalopram or one of its salts that comprises the purification of citalopram by selective extractions of citalopram or of its impurities with organic solvents and water under specific conditions of pH and temperature. The crude citalopram can be prepared by a process t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YOLANDA GASANZ GUILLEN, JULIO CAMPON PADRO, LAURA COPPI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Process for preparing purified citalopram or one of its salts that comprises the purification of citalopram by selective extractions of citalopram or of its impurities with organic solvents and water under specific conditions of pH and temperature. The crude citalopram can be prepared by a process that comprises making 1-Ä3-(dimethylamine)propylÜ-1-(4-fluorophenyl)-1,3-dihydro-5-bromoisobenzofuran react with copper cyanide.