Benzimidazoles useful as protein kinase inhibitors

Benzimidazoles useful as protein kinase inhibitors

Disclosed are substituted benzimidazole compounds of formula(I):wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention are useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are pro...

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Bibliographische Detailangaben
Hauptverfasser: JINBO LEE, SARKO, CHRISTOPHER, RONALD, WILSON, NOEL, STEWART, PULLEN, STEVEN, S, SNOW, ROGER, JOHN, ROTH, GREGORY, PAUL, CHARLES CYWIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed are substituted benzimidazole compounds of formula(I):wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention are useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.