Novel petides as NS3-serine protease inhibitors of hepatitis C virus
The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorder...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | JINPING L. MC CORMICK SUSAN Y. TAMURA YI-TSUNG LIU RUSSEL E. PIKE SCOTT JEFFREY KEMP MARGUERITA LIM-WILBY ASHOK ARASAPPAN RAYMOND G. LOVEY SRIKANTH VENKATRAMAN KEVIN X. CHEN HENRY A. VACCARO TIN-YAU CHAN ZHAONING ZHU STEPHANE L. BOGEN ODILE ESTHER LEVY FRANK BENNETT EDWIN E. JAO HAIYAN WANG TEJAL N. PAREKH F. GEORGE NJOROGE PATRICK A. PINTO VIYYOR MOOPIL GIRIJAVALLABHAN ANIL K. SAKSENA BAMA SANTHANAM ASHIT K. GANGULY |
| description | The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_ZA200210311B</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ZA200210311B</sourcerecordid><originalsourceid>FETCH-epo_espacenet_ZA200210311B3</originalsourceid><addsrcrecordid>eNqNyjEOwjAMBdAsDAi4gzlApaQ5ARQQUxeYWCoDv6qlKoli0_OzcACmt7y1O_V5wUwFJm8osVJ_i42iSgKVmg2sIEmTPMVyVcojTShsYqLU0SL1o1u3GnlW7H5u3P5yvnfXBiUP0MIvJNjwOLTet8HHEI7xn_MFckAyPA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Novel petides as NS3-serine protease inhibitors of hepatitis C virus</title><source>esp@cenet</source><creator>JINPING L. MC CORMICK ; SUSAN Y. TAMURA ; YI-TSUNG LIU ; RUSSEL E. PIKE ; SCOTT JEFFREY KEMP ; MARGUERITA LIM-WILBY ; ASHOK ARASAPPAN ; RAYMOND G. LOVEY ; SRIKANTH VENKATRAMAN ; KEVIN X. CHEN ; HENRY A. VACCARO ; TIN-YAU CHAN ; ZHAONING ZHU ; STEPHANE L. BOGEN ; ODILE ESTHER LEVY ; FRANK BENNETT ; EDWIN E. JAO ; HAIYAN WANG ; TEJAL N. PAREKH ; F. GEORGE NJOROGE ; PATRICK A. PINTO ; VIYYOR MOOPIL GIRIJAVALLABHAN ; ANIL K. SAKSENA ; BAMA SANTHANAM ; ASHIT K. GANGULY</creator><creatorcontrib>JINPING L. MC CORMICK ; SUSAN Y. TAMURA ; YI-TSUNG LIU ; RUSSEL E. PIKE ; SCOTT JEFFREY KEMP ; MARGUERITA LIM-WILBY ; ASHOK ARASAPPAN ; RAYMOND G. LOVEY ; SRIKANTH VENKATRAMAN ; KEVIN X. CHEN ; HENRY A. VACCARO ; TIN-YAU CHAN ; ZHAONING ZHU ; STEPHANE L. BOGEN ; ODILE ESTHER LEVY ; FRANK BENNETT ; EDWIN E. JAO ; HAIYAN WANG ; TEJAL N. PAREKH ; F. GEORGE NJOROGE ; PATRICK A. PINTO ; VIYYOR MOOPIL GIRIJAVALLABHAN ; ANIL K. SAKSENA ; BAMA SANTHANAM ; ASHIT K. GANGULY</creatorcontrib><description>The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.</description><edition>7</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040319&DB=EPODOC&CC=ZA&NR=200210311B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040319&DB=EPODOC&CC=ZA&NR=200210311B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JINPING L. MC CORMICK</creatorcontrib><creatorcontrib>SUSAN Y. TAMURA</creatorcontrib><creatorcontrib>YI-TSUNG LIU</creatorcontrib><creatorcontrib>RUSSEL E. PIKE</creatorcontrib><creatorcontrib>SCOTT JEFFREY KEMP</creatorcontrib><creatorcontrib>MARGUERITA LIM-WILBY</creatorcontrib><creatorcontrib>ASHOK ARASAPPAN</creatorcontrib><creatorcontrib>RAYMOND G. LOVEY</creatorcontrib><creatorcontrib>SRIKANTH VENKATRAMAN</creatorcontrib><creatorcontrib>KEVIN X. CHEN</creatorcontrib><creatorcontrib>HENRY A. VACCARO</creatorcontrib><creatorcontrib>TIN-YAU CHAN</creatorcontrib><creatorcontrib>ZHAONING ZHU</creatorcontrib><creatorcontrib>STEPHANE L. BOGEN</creatorcontrib><creatorcontrib>ODILE ESTHER LEVY</creatorcontrib><creatorcontrib>FRANK BENNETT</creatorcontrib><creatorcontrib>EDWIN E. JAO</creatorcontrib><creatorcontrib>HAIYAN WANG</creatorcontrib><creatorcontrib>TEJAL N. PAREKH</creatorcontrib><creatorcontrib>F. GEORGE NJOROGE</creatorcontrib><creatorcontrib>PATRICK A. PINTO</creatorcontrib><creatorcontrib>VIYYOR MOOPIL GIRIJAVALLABHAN</creatorcontrib><creatorcontrib>ANIL K. SAKSENA</creatorcontrib><creatorcontrib>BAMA SANTHANAM</creatorcontrib><creatorcontrib>ASHIT K. GANGULY</creatorcontrib><title>Novel petides as NS3-serine protease inhibitors of hepatitis C virus</title><description>The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyjEOwjAMBdAsDAi4gzlApaQ5ARQQUxeYWCoDv6qlKoli0_OzcACmt7y1O_V5wUwFJm8osVJ_i42iSgKVmg2sIEmTPMVyVcojTShsYqLU0SL1o1u3GnlW7H5u3P5yvnfXBiUP0MIvJNjwOLTet8HHEI7xn_MFckAyPA</recordid><startdate>20040319</startdate><enddate>20040319</enddate><creator>JINPING L. MC CORMICK</creator><creator>SUSAN Y. TAMURA</creator><creator>YI-TSUNG LIU</creator><creator>RUSSEL E. PIKE</creator><creator>SCOTT JEFFREY KEMP</creator><creator>MARGUERITA LIM-WILBY</creator><creator>ASHOK ARASAPPAN</creator><creator>RAYMOND G. LOVEY</creator><creator>SRIKANTH VENKATRAMAN</creator><creator>KEVIN X. CHEN</creator><creator>HENRY A. VACCARO</creator><creator>TIN-YAU CHAN</creator><creator>ZHAONING ZHU</creator><creator>STEPHANE L. BOGEN</creator><creator>ODILE ESTHER LEVY</creator><creator>FRANK BENNETT</creator><creator>EDWIN E. JAO</creator><creator>HAIYAN WANG</creator><creator>TEJAL N. PAREKH</creator><creator>F. GEORGE NJOROGE</creator><creator>PATRICK A. PINTO</creator><creator>VIYYOR MOOPIL GIRIJAVALLABHAN</creator><creator>ANIL K. SAKSENA</creator><creator>BAMA SANTHANAM</creator><creator>ASHIT K. GANGULY</creator><scope>EVB</scope></search><sort><creationdate>20040319</creationdate><title>Novel petides as NS3-serine protease inhibitors of hepatitis C virus</title><author>JINPING L. MC CORMICK ; SUSAN Y. TAMURA ; YI-TSUNG LIU ; RUSSEL E. PIKE ; SCOTT JEFFREY KEMP ; MARGUERITA LIM-WILBY ; ASHOK ARASAPPAN ; RAYMOND G. LOVEY ; SRIKANTH VENKATRAMAN ; KEVIN X. CHEN ; HENRY A. VACCARO ; TIN-YAU CHAN ; ZHAONING ZHU ; STEPHANE L. BOGEN ; ODILE ESTHER LEVY ; FRANK BENNETT ; EDWIN E. JAO ; HAIYAN WANG ; TEJAL N. PAREKH ; F. GEORGE NJOROGE ; PATRICK A. PINTO ; VIYYOR MOOPIL GIRIJAVALLABHAN ; ANIL K. SAKSENA ; BAMA SANTHANAM ; ASHIT K. GANGULY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ZA200210311B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2004</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>JINPING L. MC CORMICK</creatorcontrib><creatorcontrib>SUSAN Y. TAMURA</creatorcontrib><creatorcontrib>YI-TSUNG LIU</creatorcontrib><creatorcontrib>RUSSEL E. PIKE</creatorcontrib><creatorcontrib>SCOTT JEFFREY KEMP</creatorcontrib><creatorcontrib>MARGUERITA LIM-WILBY</creatorcontrib><creatorcontrib>ASHOK ARASAPPAN</creatorcontrib><creatorcontrib>RAYMOND G. LOVEY</creatorcontrib><creatorcontrib>SRIKANTH VENKATRAMAN</creatorcontrib><creatorcontrib>KEVIN X. CHEN</creatorcontrib><creatorcontrib>HENRY A. VACCARO</creatorcontrib><creatorcontrib>TIN-YAU CHAN</creatorcontrib><creatorcontrib>ZHAONING ZHU</creatorcontrib><creatorcontrib>STEPHANE L. BOGEN</creatorcontrib><creatorcontrib>ODILE ESTHER LEVY</creatorcontrib><creatorcontrib>FRANK BENNETT</creatorcontrib><creatorcontrib>EDWIN E. JAO</creatorcontrib><creatorcontrib>HAIYAN WANG</creatorcontrib><creatorcontrib>TEJAL N. PAREKH</creatorcontrib><creatorcontrib>F. GEORGE NJOROGE</creatorcontrib><creatorcontrib>PATRICK A. PINTO</creatorcontrib><creatorcontrib>VIYYOR MOOPIL GIRIJAVALLABHAN</creatorcontrib><creatorcontrib>ANIL K. SAKSENA</creatorcontrib><creatorcontrib>BAMA SANTHANAM</creatorcontrib><creatorcontrib>ASHIT K. GANGULY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JINPING L. MC CORMICK</au><au>SUSAN Y. TAMURA</au><au>YI-TSUNG LIU</au><au>RUSSEL E. PIKE</au><au>SCOTT JEFFREY KEMP</au><au>MARGUERITA LIM-WILBY</au><au>ASHOK ARASAPPAN</au><au>RAYMOND G. LOVEY</au><au>SRIKANTH VENKATRAMAN</au><au>KEVIN X. CHEN</au><au>HENRY A. VACCARO</au><au>TIN-YAU CHAN</au><au>ZHAONING ZHU</au><au>STEPHANE L. BOGEN</au><au>ODILE ESTHER LEVY</au><au>FRANK BENNETT</au><au>EDWIN E. JAO</au><au>HAIYAN WANG</au><au>TEJAL N. PAREKH</au><au>F. GEORGE NJOROGE</au><au>PATRICK A. PINTO</au><au>VIYYOR MOOPIL GIRIJAVALLABHAN</au><au>ANIL K. SAKSENA</au><au>BAMA SANTHANAM</au><au>ASHIT K. GANGULY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Novel petides as NS3-serine protease inhibitors of hepatitis C virus</title><date>2004-03-19</date><risdate>2004</risdate><abstract>The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_ZA200210311B |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | Novel petides as NS3-serine protease inhibitors of hepatitis C virus |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T00%3A00%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=JINPING%20L.%20MC%20CORMICK&rft.date=2004-03-19&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EZA200210311B%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |