Novel petides as NS3-serine protease inhibitors of hepatitis C virus

The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorder...

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Bibliographische Detailangaben
Hauptverfasser:	JINPING L. MC CORMICK, SUSAN Y. TAMURA, YI-TSUNG LIU, RUSSEL E. PIKE, SCOTT JEFFREY KEMP, MARGUERITA LIM-WILBY, ASHOK ARASAPPAN, RAYMOND G. LOVEY, SRIKANTH VENKATRAMAN, KEVIN X. CHEN, HENRY A. VACCARO, TIN-YAU CHAN, ZHAONING ZHU, STEPHANE L. BOGEN, ODILE ESTHER LEVY, FRANK BENNETT, EDWIN E. JAO, HAIYAN WANG, TEJAL N. PAREKH, F. GEORGE NJOROGE, PATRICK A. PINTO, VIYYOR MOOPIL GIRIJAVALLABHAN, ANIL K. SAKSENA, BAMA SANTHANAM, ASHIT K. GANGULY
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.