Polymorphic forms/hydrates of N-[4(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxyl)-quinazolin-6-yl]-acrylamide

There are described polymorphic forms/hydrates of N-[4-(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide dihydrochloride, processes for their preparation, as well as the use of the same for the preparation of medicaments with irreversible tyrosine kinase inhibit...

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Hauptverfasser: HUBERT BARTH, ANDREAS MUEHLENFELD, SIMON SCHNEIDER, DIETMAR HUELS, MANFRED WESTERMAYER, KLAUS STEINER
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creator HUBERT BARTH
ANDREAS MUEHLENFELD
SIMON SCHNEIDER
DIETMAR HUELS
MANFRED WESTERMAYER
KLAUS STEINER
description There are described polymorphic forms/hydrates of N-[4-(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide dihydrochloride, processes for their preparation, as well as the use of the same for the preparation of medicaments with irreversible tyrosine kinase inhibiting action.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Polymorphic forms/hydrates of N-[4(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxyl)-quinazolin-6-yl]-acrylamide
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