Polymorphic forms/hydrates of N-[4(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxyl)-quinazolin-6-yl]-acrylamide

Polymorphic forms/hydrates of N-[4(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxyl)-quinazolin-6-yl]-acrylamide

There are described polymorphic forms/hydrates of N-[4-(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide dihydrochloride, processes for their preparation, as well as the use of the same for the preparation of medicaments with irreversible tyrosine kinase inhibit...

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Bibliographische Detailangaben
Hauptverfasser: HUBERT BARTH, ANDREAS MUEHLENFELD, SIMON SCHNEIDER, DIETMAR HUELS, MANFRED WESTERMAYER, KLAUS STEINER
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:There are described polymorphic forms/hydrates of N-[4-(3-chloro-4-fluorophenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide dihydrochloride, processes for their preparation, as well as the use of the same for the preparation of medicaments with irreversible tyrosine kinase inhibiting action.