PROCESS FOR MAKING NEW DERIVATIVES 1,1,2,2-TETRAMETHYL-1,2-BIS-(2-FLUORINE-4-HYDROXI-PHENYL)-ETHAN

Antitumor compounds corresponding to the following formula: I in which the substituents R1 and R2 may be the same or different and represent hydrogen, an aminocarbonyl group, a C1-C6 alkylaminocarbonyl group, a di-C1-C6-alkylaminocarbonyl group, the group PO(OH)2, a C2-C8 alkanoyl group, a C2-C8 hal...

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Hauptverfasser: SCHOENENBERGER H, SCHWARZ W, ENGEL J, HARTMAAN R.W, SCHNEIDER M
Format: Patent
Sprache:eng
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Zusammenfassung:Antitumor compounds corresponding to the following formula: I in which the substituents R1 and R2 may be the same or different and represent hydrogen, an aminocarbonyl group, a C1-C6 alkylaminocarbonyl group, a di-C1-C6-alkylaminocarbonyl group, the group PO(OH)2, a C2-C8 alkanoyl group, a C2-C8 halogen alkanoyl group or a C3-C8 alkenoyl group, a process for their preparation, and their use in treating oestrogen-receptor-positive-tumors as well as the prostate carcinoma.