POSTUPAK ZA DOBIJANJE NOVIH BIS-(1H-INDOL-3-IL)-MALEINIMID DERIVATA

POSTUPAK ZA DOBIJANJE NOVIH BIS-(1H-INDOL-3-IL)-MALEINIMID DERIVATA

POSTUPAK ZA DOBIJANJE NOVIH BIS-(1H-INDOL-3-IL)-MALEINIMID DERIVATA. Opisani su bis-(1H-indol-3-il)-maleinimidni derivati formule (I) u kojoj R1 i/ili R2 predstavljaju vodonik, metil, etil i n-propil, R3, R6, R7 i R10 vodonik, R4, R5, R8 i R9 nezavisno predstavljaju vodonik ili halogen i njihove far...

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Hauptverfasser: OSWALD, HARTMUT, RUDOLPH, CLAUS, SCHAECHTELE, CHRISTOPH, BETCHE, HANS-JURGEN, RECK, REINHARD, BARTH, HUBERT, HARTENSTEIN, JOHANNES
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:POSTUPAK ZA DOBIJANJE NOVIH BIS-(1H-INDOL-3-IL)-MALEINIMID DERIVATA. Opisani su bis-(1H-indol-3-il)-maleinimidni derivati formule (I) u kojoj R1 i/ili R2 predstavljaju vodonik, metil, etil i n-propil, R3, R6, R7 i R10 vodonik, R4, R5, R8 i R9 nezavisno predstavljaju vodonik ili halogen i njihove farmakološki prihvatljive soli, postupci za dobijanje tih jedinjenja i farmaceutski preparati koji ih sadrže za tretiranje srčanih oboljenja i bolesti krvnih sudova, kao što je tromboza, arterioskleroza, hipertenzija, za tretiranje inflamatornih procesa, alergije, kancera i odredjenih degenerativnih oštećenja centralnog nervnog sistema, kao i bolesti imunog sistema i virusnih bolesti. The invention relates to novel bis(1H-indol-3-yl)maleimide derivatives, a process for their preparation, pharmaceuticals containing these compounds and their use for the treatment of cardiac and vascular diseases such as thromboses, arteriosclerosis, hypertension, inflammatory processes, allergies, cancer and certain types of degenerative damage of the central nervous system and also disorders of the immune system and viral diseases.