PROCESS FOR OBTAINING OF ANHYDROUS TRANSDERMAL PREPARATION

Postupak za dobijanje anhidrovanog transdermalnog preparata, naznačen time, što se 5-15% mas. optički aktivnog ili racemskog N-metil-N-(fenil-2-propil)-2-propinilamina ili N-metil-N-(1-(4-fluoro-fenil)-2-propil)-2-propinilamina ili njihove podesne soli inkorporira u smešu koja se sastoji od 40-70 ma...

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Bibliographische Detailangaben
Hauptverfasser:	TOTH, ANTAL DR, MARMAROSI, KELLNER KATALIN, MAGYAR, KALMAN DR, SZEGO, ANDRAD DR, SZABO, Z. ANNA, SZUTS, TAMAS DR, LENGYEL, JOZSEF DR, SZABO, UJHELYI GABRIELLA, SZEKELY, ANNA, PINTER, JANOS DR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	Postupak za dobijanje anhidrovanog transdermalnog preparata, naznačen time, što se 5-15% mas. optički aktivnog ili racemskog N-metil-N-(fenil-2-propil)-2-propinilamina ili N-metil-N-(1-(4-fluoro-fenil)-2-propil)-2-propinilamina ili njihove podesne soli inkorporira u smešu koja se sastoji od 40-70 mas. % tečnog polioksietilenglikola, 10-20 mas. % čvrstog polioksietilenglikola, 2-30 mas. % nejonskog površinski aktivnog sredstva, 2-20 mas. % propilenglikola i po potrebi mogu se dodati druga pomoćna sredstva. The invention concerns an anhydrous transdermal preparation comprising in a 20-100% lyotropic liquid crystalline arrangement: 5-15 w.% of optically active or racemic N-methyl-N-(phenyl-2-propyl)-2-propynylamine or N-methyl-N-(1-(4-fluoro-phenyl)-2-propyl)-2-propynylamine or their therapeutically acceptable salts, 40-70 w.% of liquid polyoxyethyleneglycol, 10-20 w.% of solid polyoxyethyleneglycol, 2-30 w.% of a nonionic surface active agent, 2-20 w.% of propyleneglycol, if desired 0.5-2 w.% of a polymer the a value of which is > 0.6, and if desired other auxiliary agents.