3,4-DI-(HIDRO)-2H,6H-PIRIMIDO (2,1-b)(1,3) TIAZIN DERIVATII1,2,3,4-TETRA-(HIDRO)-PIRIMIDIN.2.TIONI I POSTUPCI ZA NJIHOVO DOBIJANJE

3,4-DI-(HIDRO)-2H,6H-PIRIMIDO (2,1-b)(1,3) TIAZIN DERIVATII1,2,3,4-TETRA-(HIDRO)-PIRIMIDIN.2.TIONI I POSTUPCI ZA NJIHOVO DOBIJANJE, 3,4-di-(hidro)2H,6H-pirimido (2,1-b)(1,3) tiazin-derivati opšte formule I, gde R1 je C1-6 alkoksi, amino ili fenilamino R2 je C1-6 alkil ili fenil, R3 je vodonik ili C1-6 alkil, i R4 označava C1-11 alkil ili fenil koji po izboru nosi jedan ili više identičnih ili različitih supstituenata odabranih od halogena, nitro, amino di-(C1-6 alkil)amino, C1-6 alkil, C1-6 alkoksi i hidroksi, i farmaceutski prihvatljive njihove kiselinske adicione soli. Prijava sadrži još 3 nezavisna i 13 zavisnih zahteva. The invention relates to new dihydropyrimidothiazine derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same and new intermediates useful in the preparation of the said dihydropyrimidothiazine derivatives. The new dihydropyrimidothiazine derivatives of the general formula I, I wherein R1 represents C1-6 alkoxy, amino or phenylamino, R2 stands for C1-6 alkyl or phenyl, R3 represents hydrogen or C1-6 alkyl, and R4 denotes C1-11 alkyl or phenyl optionally bearing one or more identical or different substituent/s/ selected from halogen, nitro, amino, di-(C1-6 alkyl)-amino, C1-6 alkyl, C1-6 alkoxy and hydroxy, and pharmaceutically acceptable acid addition salts thereof exert valuable antianginal and/or antiinflammatory effect/s/ and are useful in therapy.