PROCESS FOR MAKING 1,4-DIHYDRO-PYRIDINIC DERIVATIVES

PROCESS FOR MAKING 1,4-DIHYDRO-PYRIDINIC DERIVATIVES

The invention is directed to processes for the preparation of dimethyl-1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dica rboxylate by reacting 1-methoxy-1-(2'-nitrophenyl)-N-(2'-nitrophenyl)methylene methanamie or 1-(2'-nitrophenyl)-N,N'-bis-(2'-nitrophenyl)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FURDYGA E, KOVANYI G, POCZIKE E, BOZSING D, MIKITE G, GOERGENYI F, IOEMPE P, IMPRE J, LEVAI L, TAJTHY E, SIMONYI I, NAGY K, KISS E, BENKO P, DINNYES I, ZALAVARI G, BECK I, MANDI A
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The invention is directed to processes for the preparation of dimethyl-1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-pyridine-3,5-dica rboxylate by reacting 1-methoxy-1-(2'-nitrophenyl)-N-(2'-nitrophenyl)methylene methanamie or 1-(2'-nitrophenyl)-N,N'-bis-(2'-nitrophenyl) methylene methanediamine with methyl acetoacetate in the presence of an amine compound or by reacting the monomeric or trimeric from of 2-nitrobenzaldimine with methyl acetoacetate.