PROCESS FOR OBTAINING NEW COMPOUNDS POSSESSING ANALGETIC ACTIVITY AFTER PARENTERAL APPLICATION

Compounds of the general formulaand pharmaceutically acceptable non-toxic acid addition salts thereof, in which L and D, when applicable, define the chirality;R1 and R2 independently are hydrogen or C1-C3 primary alkyl;R3 is C1-C3 primary or secondary alkyl or-CH2CH2-S-CH3;R4 is hydrogen or C1-C3 pr...

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Bibliographische Detailangaben
Hauptverfasser:	SHUMAN R.T, SMITHWICK E.L, FREDERICKSON R.C.A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Compounds of the general formulaand pharmaceutically acceptable non-toxic acid addition salts thereof, in which L and D, when applicable, define the chirality;R1 and R2 independently are hydrogen or C1-C3 primary alkyl;R3 is C1-C3 primary or secondary alkyl or-CH2CH2-S-CH3;R4 is hydrogen or C1-C3 primary alkyl;R5 is hydrogen or C1-C3 primary alkyl;Y is hydrogen or acetyl; andZis-CH2OH, or -CN; subject to the limitation thatone of R4 and R, is C1-C3 primary alkyl and the other is hydrogen; are useful analgesic agents.