PROCESS FOR PREPARING N-(N'-(2-CHLOROETHYL)-N'-NITROSOCARBAMOYL)-OLIGOPEPTIDE ESTERS OR AMIDES

PROCESS FOR PREPARING N-(N'-(2-CHLOROETHYL)-N'-NITROSOCARBAMOYL)-OLIGOPEPTIDE ESTERS OR AMIDES

Compounds having the formula: wherein: R4 = -OCH3, -NH2, NH-R4, R4 being an oligopeptidic residue of which the terminal carboxyl group is blocked as a methyl ester or amide group. They are prepared by reacting the corresponding aminoacids or oligopeptides with an ester or an amide of a second aminoa...

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Bibliographische Detailangaben
Hauptverfasser: EINSENBRAND G, TANG W, ZELESNY O
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Compounds having the formula: wherein: R4 = -OCH3, -NH2, NH-R4, R4 being an oligopeptidic residue of which the terminal carboxyl group is blocked as a methyl ester or amide group. They are prepared by reacting the corresponding aminoacids or oligopeptides with an ester or an amide of a second aminoacid or of a second oligopeptide, in presence of an appropriate basic peptidic catalyst.