NOVI DERIVATI PURINA

NOVI DERIVATI PURINA, jedinjenja formule u kojoj R1, R2, R3, R4, R5 i R6 imaju značenje dato u zahtevu 1, sprečavaju angiotenzin II-receptore i otuda se mogu primeniti u obliku farmaceutskih preparata pri suzbijanju odnosno sprečavanju visokog krvnog pritiska i arterioskleroze. Ona se mogu dobiti reakcijom N-bifenil-metilovanja odgovarajuće nesupstituisanih derivata purina prema po sebi poznatim metodama. The Hornus games stick has a fibre-reinforced plastic intermediate piece (2) detachably joined to the handle (1) and between the handle and the hitting part. The intermediate piece has a connection (4) with a threaded pin (7). The handle has an internal thread (9) matching the pin. The fibre-reinforced plastic handle is stuck into a metal sleeve (8) with an internal thread (9) matching the pin. The intermediate piece is stuck in the connection. USE/ADVANTAGE - The Hornus-game stick can be replaced on the spot, i.e. during a match, by means of an intermediate piece.