FLUORESCENT POLARIZATION DETECTION IN MICROFLUIDIC SYSTEMS

Fluorescent polarization assays are used in microfluidic systems to perform molecular binding assays and to screen for potential affectors of the molecular binding functions. The fluorescent polarization assays are performed in an entirely homogeneous assay format and are generally performed in a co...

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Bibliographische Detailangaben
Hauptverfasser:	LEE, ERNEST, C., W, SUNDBERG, STEVEN, A, CHAUDHURI, DIPANKAR, PARCE, J., WALLACE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS TESTING TRANSPORTING
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Beschreibung
Zusammenfassung:	Fluorescent polarization assays are used in microfluidic systems to perform molecular binding assays and to screen for potential affectors of the molecular binding functions. The fluorescent polarization assays are performed in an entirely homogeneous assay format and are generally performed in a continuously flowing channel of a microfluidic device. L'invention concerne des analyses de polarisation fluorescente utilisées dans des systèmes microfluidiques afin d'effectuer des analyses de liaison moléculaire, et de détecter par criblage des agents pouvant potentiellement altérer les fonctions de liaison moléculaire. Ces analyses de polarisation fluorescente, effectuées selon une technique d'analyse entièrement homogène, sont généralement menées dans un canal d'écoulement continu d'un dispositif microfluidique.