POLYPEPTIDES WITH BETA-SECRETASE TYPE ACTIVITY

The invention concerns novel peptides and their pharmaceutical use. More particularly, the invention concerns novel polypeptides having a beta -secretase type activity characterised in that they are capable of specifically cleaving the natural beta -amyloid peptide precursor (APP). La présente inven...

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Bibliographische Detailangaben
Hauptverfasser:	RHOLAM, MOHAMED, MUNOZ-GIMENEZ, NOELI, MOUTAOUAKIL, MOHAMED, COHEN, PAUL, BERTRAND, PHILIPPE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention concerns novel peptides and their pharmaceutical use. More particularly, the invention concerns novel polypeptides having a beta -secretase type activity characterised in that they are capable of specifically cleaving the natural beta -amyloid peptide precursor (APP). La présente invention concerne de nouveaux polypeptides et leur utilisation pharmaceutique. Plus particulièrement, la présente invention concerne de nouveaux polypeptides possédant une activité de type beta -secrétase caractérisés en ce qu'ils sont capables de cliver de manière spécifique le précurseur naturel du peptide beta -amyloïde (APP).