COLLAGEN PEPTIDES AND USES THEREOF

Collagen peptides, fragments and variants are able to interact with and/or bind integrin alpha 2 beta 1, integrin alpha 1 beta 1 and/or platelet receptor GpVI. Such peptides, mimetics thereof and substances that bind them are useful in modulating platelet and other cell function, including aggregati...

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Hauptverfasser: FARNDALE, RICHARD, WILLIAM, BARNES, MICHAEL, JOHN
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BARNES, MICHAEL, JOHN
description Collagen peptides, fragments and variants are able to interact with and/or bind integrin alpha 2 beta 1, integrin alpha 1 beta 1 and/or platelet receptor GpVI. Such peptides, mimetics thereof and substances that bind them are useful in modulating platelet and other cell function, including aggregation and activation. L'invention concerne des peptides, des fragments et des variantes de collagène capables d'interagir et/ou de se lier avec l'intégrine alpha 2 beta 1, l'intégrine alpha 1 beta 1, et/ou le récepteur GpVI des plaquettes. Ces peptides, des mimétiques de ces peptides et des substances liant ces peptides sont utiles dans la modulation plaquettaire et autres fonctions cellulaires, notamment l'agrégation et l'activation.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
title COLLAGEN PEPTIDES AND USES THEREOF
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