NOVEL GABAB RECEPTOR DNA SEQUENCES

DNA encoding a novel human GABAB receptor subunit, HG20, as well as the protein encoded by the DNA, is provided. Also provided is DNA encoding a novel murine GABAB receptor subunit, GABABR1a, as well as the protein encoded by the DNA. Heterodimers of HG20 protein and GABABR1a protein that form a fun...

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Hauptverfasser: MCDONALD, TERRENCE, CLARK, JANET, NG, GORDON, YIU, KON, BONNERT, TIMOTHY, P, BONNER, TOM, I, LIU, QUINGYUN, KOLAKOWSKI, LEE, F., JR
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creator MCDONALD, TERRENCE
CLARK, JANET
NG, GORDON, YIU, KON
BONNERT, TIMOTHY, P
BONNER, TOM, I
LIU, QUINGYUN
KOLAKOWSKI, LEE, F., JR
description DNA encoding a novel human GABAB receptor subunit, HG20, as well as the protein encoded by the DNA, is provided. Also provided is DNA encoding a novel murine GABAB receptor subunit, GABABR1a, as well as the protein encoded by the DNA. Heterodimers of HG20 protein and GABABR1a protein that form a functional GABAB receptor are disclosed. Methods of identifying agonists and antagonists of the GABAB receptor are also provided. La présente invention concerne de l'ADN codant une nouvelle sous-unité du récepteur GABAB humain, HG20, ainsi que la protéine codée par ledit ADN. Elle concerne également un ADN codant une nouvelle sous-unité de récepteur GABAB murin, GABABR1a, ainsi que la protéine codée par ledit ADN. Elle concerne encore des hétérodimères de la protéine HG20 et de la protéine GABABR1a qui forment un récepteur GABAB fonctionnel, ainsi que des procédés d'identification d'agonistes et d'antagonistes du récepteur GABAB.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
TESTING
VINEGAR
WINE
title NOVEL GABAB RECEPTOR DNA SEQUENCES
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