EMULSIONS FOR AEROSOLIZATION AND DRUG DELIVERY

EMULSIONS FOR AEROSOLIZATION AND DRUG DELIVERY

Compositions containing drug- or therapeutic agent-containing solutions and fluorocarbons are disclosed for pulmonary delivery of the drug or therapeutic agent. Suitable fluorocarbons have relatively high vapor pressures or corresponding low boiling points, preferably between about -30 DEG to about...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LAI, JOHNNY, QUAY, STEVEN, C, KESSLER, DEAN, R
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Compositions containing drug- or therapeutic agent-containing solutions and fluorocarbons are disclosed for pulmonary delivery of the drug or therapeutic agent. Suitable fluorocarbons have relatively high vapor pressures or corresponding low boiling points, preferably between about -30 DEG to about 150 DEG C, and include dodecafluoropentane, dodecafluoroneopentane, perfluorocyclopentane, perfluoro-2-methyl pentane, perfluorohexane, perfluoroheptane, perfluorooctane, perfluorodecalin and isomers and mixtures thereof. Aerosolized emulsions of these fluorocarbons produce fine aerosol particles of