dsRNA/dsRNA-BINDING PROTEIN METHODS AND COMPOSITIONS

Disclosed is a screening method for identifying compounds capable of disrupting binding of a dsRNA-binding protein or protein complex to dsRNA. Also disclosed are methods of treating viral infections using such compounds. L'invention concerne un procédé de criblage servant à identifier des comp...

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Bibliographische Detailangaben
Hauptverfasser:	EDWARDS, CYNTHIA, A, TURIN, LISA, M, BELYAEV, ALEXANDER, S, BRUICE, THOMAS, WAYNE, FRY, KIRK, E
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed is a screening method for identifying compounds capable of disrupting binding of a dsRNA-binding protein or protein complex to dsRNA. Also disclosed are methods of treating viral infections using such compounds. L'invention concerne un procédé de criblage servant à identifier des composés capables d'interrompre la fixation d'une protéine de fixation ou d'un complexe protéinique d'ARN bicaténaire à un ARN bicaténaire. L'invention concerne également des méthodes de traitement d'infections virales au moyen de ces composés.