ENHANCEMENT OF MUCOSAL ANTIBODY RESPONSES BY INTERLEUKIN-6

The invention provides a transgenic mouse overexpressing human interleukin-6 and methods of enhancing mucosal IgA responses in which interleukin-6 is delivered to the mucosal immune system. These methods are useful in preventing infectious diseases. L'invention a trait à une souris transgénique...

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1. Verfasser:	DERMAN, EVA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a transgenic mouse overexpressing human interleukin-6 and methods of enhancing mucosal IgA responses in which interleukin-6 is delivered to the mucosal immune system. These methods are useful in preventing infectious diseases. L'invention a trait à une souris transgénique surexprimant l'interleukine-6 humaine, et à des procédés permettant d'améliorer l'élaboration d'anticorps IgA de muqueuses, dans lesquels l'interleukine-6 est administrée au système immunitaire des muqueuses. Les procédés sont utiles pour prévenir des maladies infectieuses.