PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS

This invention relates to the use of a compound of formula (1) where: R is hydrogen, halogen, hydroxy, azido, alkoxy, aryloxy, thio, alkylthio, amino, alkylamino, hydrazino, hydroxylamino, benzyloxy, NRR' or NRCOR'; R is hydrogen, halogen, hydroxy, azido, alkoxy, aryloxy, thio, alkylthio,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JARVIS, KAREN, ELIZABETH, MARCUCCIO, SEBASTIAN, MARIO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to the use of a compound of formula (1) where: R is hydrogen, halogen, hydroxy, azido, alkoxy, aryloxy, thio, alkylthio, amino, alkylamino, hydrazino, hydroxylamino, benzyloxy, NRR' or NRCOR'; R is hydrogen, halogen, hydroxy, azido, alkoxy, aryloxy, thio, alkylthio, amino, alkylamino, hydrazino, hydroxylamino, benzyloxy, NRR' or NRCOR'; and R and R' are independently selected from hydrogen, alkyl and aryl; or a salt and pharmaceutically acceptable derivatives thereof; in the treatment and/or prophylaxis of hepatitis B viral infection. L'invention concerne l'utilisation dans le traitement ou la prophylaxie de l'infection virale de l'hépatite B, d'un composé de la formule (1) ou un sel ou des dérivés pharmaceutiquement acceptables dudit composé. Dans cette formule, R désigne hydrogène, halogène, hydroxy, azido, alcoxy, arylthyo, aryloxy, thio, alkylthio, amino, alkylamino, hydrazino, hydroxylamino, benzyloxy, NRR' ou NRCOR'; R désigne hydrogène, halogène, hydroxy, azido, alcoxy, aryloxy, thio, alkylthio, amino, alkylamino, hydrazino, hydroxylamino, benzyloxy, NRR' ou NRCOR'; et R et R' sont sélectionnés indépendamment l'un de l'autre dans le groupe comprenant hydrogène, alkyle et aryle.