GASTROINTESTINAL MUCOSA-ADHERENT PHARMACEUTICAL COMPOSITION

In order to provide a composition having a long gastroduodenal residence time and exhibiting an improved efficacy, is provided a gastrointestinal mucosa-adherent composition comprising an active ingredient and a material which swells a viscogenic agent capable of being viscous with water (e.g. curdl...

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Bibliographische Detailangaben
Hauptverfasser:	KITANO, MEGUMI, NAGAHARA, NAOKI, NAKAO, MASAFUMI, AKIYAMA, YOHKO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	In order to provide a composition having a long gastroduodenal residence time and exhibiting an improved efficacy, is provided a gastrointestinal mucosa-adherent composition comprising an active ingredient and a material which swells a viscogenic agent capable of being viscous with water (e.g. curdlan and/or a low-substituted hydroxypropylcellulose, etc.). Pour obtenir une composition à long temps de séjour gastro-duodénal d'une efficacité renforcée, on a mis au point une composition adhérant à la muqueuse gastro-intestinale comportant un principe actif et une substance faisant gonfler un agent viscogène devenant visqueux en présence d'eau tel que par exemple du curdlan et/ou de l'hydroxypropyle cellulose faiblement substituée, etc.