HAEMOCOMPATIBLE SURFACES

The present invention relates to a monoclonal antibody reactive with human serum albumin (HSA) in a manner such that when the monoclonal antibody is bound to HSA, the HSA retains its ability to prevent cell attachment. The present invention also relates to the use of such an antibody in the producti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MCFARLAND, CLIVE, DAVID, UNDERWOOD, PATRICIA, ANNE, STEELE, JOHN, GERARD
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates to a monoclonal antibody reactive with human serum albumin (HSA) in a manner such that when the monoclonal antibody is bound to HSA, the HSA retains its ability to prevent cell attachment. The present invention also relates to the use of such an antibody in the production of a biomaterial such that cell colonisation of the biomaterial is minimised. La présente invention concerne un anticorps monoclonal réagissant avec l'albumine du sérum humain (HSA) d'une manière telle que lorsque l'anticorps monoclonal est fixé à HSA, la HSA conserve sa capacité d'empêcher la fixation des cellules. La présente invention concerne également l'utilisation de cet anticorps dans la production d'un biomatériau permettant de réduire au minimum la colonisation cellulaire du biomatériau.