PROCESSES AND COMPOSITIONS FOR SPRAY DRYING HYDROPHOBIC DRUGS IN ORGANIC SOLVENT SUSPENSIONS OF HYDROPHILIC EXCIPIENTS

Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions or suspensions of the components and spray drying them simultaneously in a spray drier. The hydrophobic component may be dissolved in an inorganic solvent and the hydrophilic component suspen...

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Bibliographische Detailangaben
1. Verfasser:	GORDON, MARC, S
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATION THEIR RELEVANT APPARATUS TRANSPORTING
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Zusammenfassung:	Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions or suspensions of the components and spray drying them simultaneously in a spray drier. The hydrophobic component may be dissolved in an inorganic solvent and the hydrophilic component suspended therein. The method provides dry powders having relatively uniform characeteristics. L'invention concerne des procédés de préparation de poudres anhydres renfermant des composants hydrophobes et hydrophiles. Ces procédés consistent à combiner des solutions ou des suspensions de ces composants et à les sécher simultanément par pulvérisation dans un pulvérisateur. Le composant hydrophobe peut être dissous dans un solvant organique, et le composant hydrophile mis en suspension dans ce solvant. Ce procédé permet d'obtenir des poudres anhydres présentant des caractéristiques relativement uniformes.