COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES

Novel compositions are provided. Typically, the compositions comprise one or more neutral co-lipids and also a cationic amphiphile. Therapeutic compositions are prepared according to the practice of the invention by contacting a therapeutically active molecule with a dispersion of neutral co-lipid(s...

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Hauptverfasser: MARSHALL, JOHN, LEE, EDWARD, R, EASTMAN, SIMON, J, ROWE, ERIC, A, LANE, MATHIEU, B, YEW, NELSON, S, FASBENDER, ALLEN, J, WELSH, MICHAEL, J, CHENG, SENG, H, SCHEULE, RONALD, K, CHANG, CHAU-DUNG, HARRIS, DAVID, J, SIEGEL, CRAIG, S, HUBBARD, SHIRLEY, C
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creator MARSHALL, JOHN
LEE, EDWARD, R
EASTMAN, SIMON, J
ROWE, ERIC, A
LANE, MATHIEU, B
YEW, NELSON, S
FASBENDER, ALLEN, J
WELSH, MICHAEL, J
CHENG, SENG, H
SCHEULE, RONALD, K
CHANG, CHAU-DUNG
HARRIS, DAVID, J
SIEGEL, CRAIG, S
HUBBARD, SHIRLEY, C
description Novel compositions are provided. Typically, the compositions comprise one or more neutral co-lipids and also a cationic amphiphile. Therapeutic compositions are prepared according to the practice of the invention by contacting a therapeutically active molecule with a dispersion of neutral co-lipid(s) and amphiphile(s). L'invention concerne de nouvelles compositions qui comprennent généralement un ou plusieurs co-lipides neutres ainsi qu'un amphiphile cationique. Selon cette invention, on prépare ces compositions thérapeutiques en mettant en contact une molécule thérapeutiquement active avec une dispersion de co-lipide(s) et d'amphiphile(s) neutres.
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language eng ; fre
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES
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