COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND CO-LIPIDS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES

Novel compositions are provided. Typically, the compositions comprise one or more neutral co-lipids and also a cationic amphiphile. Therapeutic compositions are prepared according to the practice of the invention by contacting a therapeutically active molecule with a dispersion of neutral co-lipid(s...

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Bibliographische Detailangaben
Hauptverfasser:	MARSHALL, JOHN, LEE, EDWARD, R, EASTMAN, SIMON, J, ROWE, ERIC, A, LANE, MATHIEU, B, YEW, NELSON, S, FASBENDER, ALLEN, J, WELSH, MICHAEL, J, CHENG, SENG, H, SCHEULE, RONALD, K, CHANG, CHAU-DUNG, HARRIS, DAVID, J, SIEGEL, CRAIG, S, HUBBARD, SHIRLEY, C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Novel compositions are provided. Typically, the compositions comprise one or more neutral co-lipids and also a cationic amphiphile. Therapeutic compositions are prepared according to the practice of the invention by contacting a therapeutically active molecule with a dispersion of neutral co-lipid(s) and amphiphile(s). L'invention concerne de nouvelles compositions qui comprennent généralement un ou plusieurs co-lipides neutres ainsi qu'un amphiphile cationique. Selon cette invention, on prépare ces compositions thérapeutiques en mettant en contact une molécule thérapeutiquement active avec une dispersion de co-lipide(s) et d'amphiphile(s) neutres.