CELL STIMULATION

Disclosed is a chimeric polypeptide for display on a cell surface, comprising an effective portion of the CD28 intracellular signalling domain, a transmembrane domain and an extracellular antigen-specific binding domain of an immunoglobulin.

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Bibliographische Detailangaben
Hauptverfasser: ALVAREZ-VALLINA, LUIS, HAWKINS, ROBERT, EDWARD
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:Disclosed is a chimeric polypeptide for display on a cell surface, comprising an effective portion of the CD28 intracellular signalling domain, a transmembrane domain and an extracellular antigen-specific binding domain of an immunoglobulin.