NAPHTHYL GLYOXAMIDES AS sPLA2 INHIBITORS

A class of novel naphthyl glyoxamide compounds is disclosed together with a process for making the novel naphthyl glyoxamide compounds and the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock. L'invention concerne une ca...

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Bibliographische Detailangaben
Hauptverfasser:	HERRON, DAVID, K, GOODSON, THEODORE, JR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A class of novel naphthyl glyoxamide compounds is disclosed together with a process for making the novel naphthyl glyoxamide compounds and the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock. L'invention concerne une catégorie de nouveaux composés de naphtylglyoxamides ainsi qu'un procédé relatif à la fabrication de ces composés et à leur utilisation pour inhiber la libération d'acides gras, induite par sPLA2, pour le traitement d'affections telle que le choc septique.