IMMUNOSUPPRESSIVE AND TUMOUR-SUPPRESSIVE BONE MARROW FACTOR

A novel immunosuppressive factor derived from mammalian bone marrow factor is described, which inhibits T lymphocyte activation and TNF- alpha production by activated macrophages and also inhibits tumour and leukemia cell growth. The factor provides a novel therapeutic composition for treatment of t...

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Bibliographische Detailangaben
1. Verfasser:	SINGHAL, SHARWAN, K
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A novel immunosuppressive factor derived from mammalian bone marrow factor is described, which inhibits T lymphocyte activation and TNF- alpha production by activated macrophages and also inhibits tumour and leukemia cell growth. The factor provides a novel therapeutic composition for treatment of tumours and of disorders associated with inflammatory reactions or T lymphocyte activation. L'invention décrit un facteur immunodépressif de type nouveau tiré de la moelle osseuse de mammifères, qui inhibe l'activation des lymphocytes T et la production de TNF- alpha par des macrophages activés, et inhibe également la croissance des cellules tumorales et leucémiques. Ledit facteur fournit une nouvelle composition thérapeutique pour le traitement de tumeurs et de troubles associés à des réactions inflammatoires ou à l'activation de lymphocytes T.