ATTENUATED CANINE PARVOVIRUS VACCINE

The invention is directed to a novel attenuated canine parvovirus (CPV) strain which may be used as a veterinary vaccine against CPV disease. The invention is further directed to a virus stock generated from a genomic DNA clone of the attenuated CPV strain which is used as a veterinary vaccine and i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	CARMICHAEL, LELAND, E, GRUENBERG, ALLEN, PARRISH, COLIN, R
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention is directed to a novel attenuated canine parvovirus (CPV) strain which may be used as a veterinary vaccine against CPV disease. The invention is further directed to a virus stock generated from a genomic DNA clone of the attenuated CPV strain which is used as a veterinary vaccine and is able to confer protective immunity to dogs against challenge with virulent CPV. Methods are given for the production of an attenuated CPV virus from a cloned CPV genome which may be used as a veterinary vaccine. L'invention concerne une nouvelle souche de parvovirus du chien atténué, utilisable comme vaccin de médecine vétérinaire contre la parvovirose canine. L'invention concerne aussi une population virale, produite à partir d'un clone génomique de la souche de parvovirus du chien atténuée, qui est utilisée comme vaccin vétérinaire et peut conférer une immunité protectrice aux chiens face à une provocation due au parvorirus virulent du chien. On décrit des procédés qui permettent de produire à partir d'un génome de parvovirus du chien cloné un parvovirus atténué pouvant être utilisé pour un vaccin vétérinaire.