ANTITHROMBOTIC AGENTS

This invention relates to L-arginine aldehyde derivatives, having formula (I) where X and Y have the values defined in the description, as well as pharmaceutical formulations containing those compounds and methods of their use as thrombin inhibitors, coagulation inhibitors, and thromboembolic disord...

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Bibliographische Detailangaben
Hauptverfasser:	SMITH, GERALD, FLOYD, SCHACHT, AARON, LEIGH, WILLEY, MICHAEL, ROBERT, CHIRGADZE, NICKOLAY, YURI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to L-arginine aldehyde derivatives, having formula (I) where X and Y have the values defined in the description, as well as pharmaceutical formulations containing those compounds and methods of their use as thrombin inhibitors, coagulation inhibitors, and thromboembolic disorder agents. L'invention concerne des dérivés d'aldéhydes de L-arginine de formule (I) où X et Y ont les valeurs définies dans la description. Elle concerne aussi des formulations pharmaceutiques contenant ces composés, et des procédés ayant trait à leur utilisation comme inhibiteurs de thrombine ou de coagulation et d'agents de traitement des troubles thromboemboliques.