NOVEL 1,2-DITHIIN ANTIINFECTIVE AGENTS

This invention pertains to a novel group of 1,2-dithiin compounds useful as antiinfective agents, and a novel synthetic process to produce the same. The compounds are particularly effective in treating fungal infections, especially those caused by Candida albicans, Cryptococcus neoformans or Aspergi...

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Bibliographische Detailangaben
Hauptverfasser:	BIERER, DONALD, E, TRUONG, THIEN, V, TEMPESTA, MICHAEL, S, KOREEDA, MASATO, HECTOR, RICHARD, DENER, JEFFREY, M, YANG, WU, LOEV, BERNARD
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention pertains to a novel group of 1,2-dithiin compounds useful as antiinfective agents, and a novel synthetic process to produce the same. The compounds are particularly effective in treating fungal infections, especially those caused by Candida albicans, Cryptococcus neoformans or Aspergillus fumigatus. L'invention a pour objet un nouveau groupe de composés de 1,2-dithiine utilisables comme agents anti-infectieux, ainsi qu'un nouveau procédé de synthèse pour produire ceux-ci. Ces composés sont particulièrement efficaces pour traiter les mycoses, en particulier celles dues à Candida albicans, Cryptococcus neoformans et Aspergillus fumigatus.