FLUORESCENT POLYMER LABELED CONJUGATES AND INTERMEDIATES

The instant invention provides a highly fluorescent conjugate which is useful in specific binding assays, and which comprises a specific binding member bound to a fluorescent polymer. The fluorescent polymer comprises a backbone polymer having multiple signal generating groups immobilized thereon an...

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Hauptverfasser: HUFF, JEFFREY, BRUCE, BIENIARZ, CHRISTOPHER
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BIENIARZ, CHRISTOPHER
description The instant invention provides a highly fluorescent conjugate which is useful in specific binding assays, and which comprises a specific binding member bound to a fluorescent polymer. The fluorescent polymer comprises a backbone polymer having multiple signal generating groups immobilized thereon and, optionally, cyclodextrin moieties in association with the polymer. Also provided is a novel process for creating 6-cyclodextrin monoaldehyde. L'invention concerne un conjugué extrêmement fluorescent présentant une efficacité dans des méthodes spécifiques d'immunodétection et comprenant un élément liant spécifique fixé à un polymère fluorescent. Le polymère fluorescent comprend un polymère squelette, sur lequel sont immobilisés des groupes multiples générateurs de signaux et, éventuellement, des fractions de cyclodextrine associées au polymère. L'invention concerne également un nouveau procédé de préparation de monoaldéhyde de 6-cyclodextrine.
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The fluorescent polymer comprises a backbone polymer having multiple signal generating groups immobilized thereon and, optionally, cyclodextrin moieties in association with the polymer. Also provided is a novel process for creating 6-cyclodextrin monoaldehyde. L'invention concerne un conjugué extrêmement fluorescent présentant une efficacité dans des méthodes spécifiques d'immunodétection et comprenant un élément liant spécifique fixé à un polymère fluorescent. Le polymère fluorescent comprend un polymère squelette, sur lequel sont immobilisés des groupes multiples générateurs de signaux et, éventuellement, des fractions de cyclodextrine associées au polymère. 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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MEASURING
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PHYSICS
POLYSACCHARIDES
TESTING
THEIR PREPARATION OR CHEMICAL WORKING-UP
title FLUORESCENT POLYMER LABELED CONJUGATES AND INTERMEDIATES
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