FLUORESCENT POLYMER LABELED CONJUGATES AND INTERMEDIATES

The instant invention provides a highly fluorescent conjugate which is useful in specific binding assays, and which comprises a specific binding member bound to a fluorescent polymer. The fluorescent polymer comprises a backbone polymer having multiple signal generating groups immobilized thereon an...

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Bibliographische Detailangaben
Hauptverfasser:	HUFF, JEFFREY, BRUCE, BIENIARZ, CHRISTOPHER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON DERIVATIVES THEREOF INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEASURING METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PHYSICS POLYSACCHARIDES TESTING THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	The instant invention provides a highly fluorescent conjugate which is useful in specific binding assays, and which comprises a specific binding member bound to a fluorescent polymer. The fluorescent polymer comprises a backbone polymer having multiple signal generating groups immobilized thereon and, optionally, cyclodextrin moieties in association with the polymer. Also provided is a novel process for creating 6-cyclodextrin monoaldehyde. L'invention concerne un conjugué extrêmement fluorescent présentant une efficacité dans des méthodes spécifiques d'immunodétection et comprenant un élément liant spécifique fixé à un polymère fluorescent. Le polymère fluorescent comprend un polymère squelette, sur lequel sont immobilisés des groupes multiples générateurs de signaux et, éventuellement, des fractions de cyclodextrine associées au polymère. L'invention concerne également un nouveau procédé de préparation de monoaldéhyde de 6-cyclodextrine.