BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS

BIS-IMIDE POLYCYCLIC AND HETEROCYCLIC CHROMOPHORES USEFUL AS TUMORICIDALS

This invention relates to bis-imide derivatives of tri- and tetraamines of formula (I), pharmaceutical compositions containing them, and methods of using them to treat cancer, particularly solid tumors, in mammals. Cette invention concerne des dérivés bis-imide de triamines et de tétraamines de la f...

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Hauptverfasser: PATTEN, ARTHUR, DAVID, CHERNEY, ROBERT, JOSEPH, PACOFSKY, GREGORY, JAMES, SEITZ, STEVEN, PAUL, AKAMIKE, EMEKA, AMAECHI, KALTENBACH, ROBERT, FRANK, III, ORWAT, MICHAEL, JAMES
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This invention relates to bis-imide derivatives of tri- and tetraamines of formula (I), pharmaceutical compositions containing them, and methods of using them to treat cancer, particularly solid tumors, in mammals. Cette invention concerne des dérivés bis-imide de triamines et de tétraamines de la formule (I), des compositions pharmaceutiques les contenant et des méthodes d'utilisation de celles-ci pour traiter le cancer, en particulier les tumeurs solides chez les mammifères.