ARYLTRIFLATES AND RELATED COMPOUNDS

Described are aryltriflates and related derivatives of raclopride, riluzole, cisapride, omeprazole, lanzoprazole, pantoprazole, paroxetine, fenfluramine, sotalol, estradiol, RU 486, tacrine, moclobemide, ifenprodil, brofaromine, melatonin, N-Acetyl-2[(7-trifluoromethylsulfonyloxy-1-naphtyl)ethyl]ami...

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Hauptverfasser: BARF, TJEERD, ANDRIES, WIKSTROEM, HAAKAN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Described are aryltriflates and related derivatives of raclopride, riluzole, cisapride, omeprazole, lanzoprazole, pantoprazole, paroxetine, fenfluramine, sotalol, estradiol, RU 486, tacrine, moclobemide, ifenprodil, brofaromine, melatonin, N-Acetyl-2[(7-trifluoromethylsulfonyloxy-1-naphtyl)ethyl]amine, prenalterol, sumatriptane, 6-substituted 3-amino-1,2,3,4-tetrahydrocarbazole, mianserin, trans-(4aS, 10bS)-7-hydroxy-4-n-Propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline and carbamazepine. The compounds are useful as drugs with, in particular for the treatment of disorders of the central nervous system. Aryltriflates et derivés connexes de raclopride, riluzole,cisapride, oméprazole, lanzaprazole, pantoprazole, paroxétine, fenfluramine, sotalol, estradiol, RU486, tacrine, moclobémide, ifenprodile,brofaromine, mélatonine, N-acétyle-2[(7-trifluoromethylsulfonyloxy-1-naphtyle)éthyl]amine, prénaltérol, sumatriptane, 3-amino-1,2,3,4-tétrahydrocarbazole à substitution en position 6, miansérine, trans-(4aS, 10bS)-7-hydroxy-4-n-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline et carbamazépine. Ces composés sont utiles comme médicaments, en particulier pour le traitement de troubles du système nerveux central.