THERAPEUTIC INHIBITION OF PLATELET AGGREGATION BY NUCLEOPHILE-NITRIC OXIDE COMPLEXES AND DERIVATIVES THEREOF

THERAPEUTIC INHIBITION OF PLATELET AGGREGATION BY NUCLEOPHILE-NITRIC OXIDE COMPLEXES AND DERIVATIVES THEREOF

A method of inhibiting platelet aggregation $i(in vivo) with physiologically compatible compounds containing at least one N-oxo-N-nitrosoamine moiety in a molecule thereof, wherein the physiologically compatible compound releases nitric oxide in a sustained and controllable fashion $i(in vivo). Proc...

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Bibliographische Detailangaben
Hauptverfasser: KEEFER, LARRY, KAY, DIODATI, JEAN, GINO
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A method of inhibiting platelet aggregation $i(in vivo) with physiologically compatible compounds containing at least one N-oxo-N-nitrosoamine moiety in a molecule thereof, wherein the physiologically compatible compound releases nitric oxide in a sustained and controllable fashion $i(in vivo). Procédé pour inhiber l'agrégation plaquettaire in vivo avec des composés physiologiquement tolérables renfermant au moins une fraction N-oxo-N-nitrosoamine dans une de leurs molécules, dans lequel le composé physiologiquement tolérable libère de l'oxyde nitrique in vivo de manière prolongée et contrôlable.